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Insulin-like Growth Factor 1 (IGF-1) and its extended variant, IGF-1 LR3, share many similarities but also exhibit distinct differences that impact their functions and applications

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In this study, glutamine flux was directed toward the generation of R-2-HG in IDH1/2 mutant cells, and the kinetics of R-2-HG formation were proportionally of the same order of magnitude as those of glutamate or -KG formation via glutaminolysis

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The SELECT cardiovascular outcomes trial further demonstrated a 20% reduction in major cardiovascular events in patients with obesity and prior cardiovascular disease