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Results Changes in testis weight, seminiferous tubule histology, and mRNA levels of spermatogenic marker genes On PND 24, following three daily administrations of rhGH, the testis weights of the 1 and 2 IU/kg rhGH rats were significantly lower than those of the control rats

Additionally, GPER influences the expression of bone metabolism-associated genes such as Runx2 and osteocalcin through downstream signaling pathways, including cAMP/PKA and AMPK, promoting osteoblast activity and suppressing osteoclast-mediated bone resorption

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A low-carbohydrate ketogenic diet can alleviate chronic musculoskeletal pain, improve blood biomarkers, and enhance the quality of life of patients (96)

Figure 1 shows the process flow of data processing in this research