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Second, contrary to CVOTs on GLP-1 RAs that included T2DM patients with established cardiovascular disease or at high cardiovascular risk, tirzepatide trials randomized T2DM patients irrespective of presence of prior cardiovascular disease or cardiovascular risk factors, a fact that may account for the very low number of recorded MACE, and possibly for type II errors

Furthermore, the gastrointestinal adverse effects commonly associated with Mounjaro, including nausea, vomiting, and diarrhoea, can lead to dehydration and electrolyte imbalances

Tirzepatide seems to be the better option. The best weight loss results, according to the meta analysis, were with the highest doses of tirzepatide

What are SARMs

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