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Recent studies have also reported that POR and CYB5R1 can transfer electrons from NAD(P)H to oxygen to generate the H 2 O 2 , which subsequently reacts with iron to generate hydroxyl radicals for further promoting the peroxidation of PUFA of PLs-PMs, thereby disrupting membrane integrity and leading to ferroptosis [40, 41]
2 The focus of the trial would be on short-term side effects and how well the drug worked to keep off the kilograms
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2020;16:e042909
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