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10.1111/jnc.70073 29 FedericiL.MasulliM.De LaurenziV.AllocatiN

In rodent models, reported effects in tendon, ligament, muscle and gastrointestinal tissue have been attributed to modulation of the VEGFR2 / nitric oxide pathway, upregulation of growth-hormone receptor expression in fibroblasts, and effects on FAKpaxillin signalling that influence cell migration

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In theory, this could support tumor vascularization