mayo clinic semaglutide researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.⁠ ⁠ The test estimates an individual's calories to satiation ( Semaglutide (GLP-1): Weight Loss Benefits

Semaglutide slows how quickly the stomach empties, delaying digestion which can lead to bloating, nausea, and vomiting

New England Journal of Medicine (2025) 6

Ozempic works by mimicking a naturally occurring hormone in body called GLP-1

The GLP-1 headache guide covers prevention and treatment Fatigue: May improve with energy-supporting strategies and adequate protein intake Hair thinning: A less common but documented side effect at higher doses, covered in our GLP-1 hair loss guide Common questions providers hear about 50 units Healthcare providers prescribing semaglutide hear certain questions repeatedly from patients drawing 50 units

In other words, the research is still developing