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Common side effects may include nausea, diarrhea, and constipation, mainly during the initial phase of treatment

These efforts would be vital to advancing GLP-1 RAs from symptomatic relief toward disease modification and personalized treatment in PD patients with metabolic dysfunction

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In the rodent high fat fed male mice model, administration of semaglutide at the dose of 2800 g/kg/day resulted in a significant weight loss attributed to a decreased food intake [70]