Although the precise cause of UC is unknown, various mechanisms, including neutrophil infiltration, high concentrations of cytokines, and reactive oxygen compounds (ROS) which promote inflammation, are designated to play a role in the pathophysiology of UC (Balmus et al
Giral P, Moulin P, Rosenbaum D
95% CI, 0.57-1.01) and those not using a GLP-1 (HR = 0.78
26,95 Diagnosis and screening recommendations Early detection of DPN is crucial to prevent foot ulcers and amputations, among other complications
An emerging concept is that cardiolipin migration to the outer membrane of the mitochondrion is the trigger that induces misfolding into soluble oligomers of various proteins present in the cytoplasm