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In animal studies, semaglutide caused these tumors, but it is not known if this risk applies to humans

It contains various bioactive substances, such as polysaccharides, phenolic compounds, fatty acids, carotenoids, and tocopherols

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Important topics include: Potential drug interactions between GLP-1 medications and DMARDs Monitoring strategies for both conditions Whether weight loss might improve RA symptoms or treatment response Cardiovascular risk reduction strategies Safety considerations including contraindications (personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2) Patients should not discontinue or modify DMARD therapy based on unproven theories about GLP-1 medications treating RA

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