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Of note, tyrosinase inhibitors identified using mh-Tyr inhibition were noted with least or no mammalian tyrosinase inhibition, because of significant difference in the catalytic activities and substrate specificities of mh-Tyr against mammalian Tyrosinase enzyme 63,114

This self-perpetuating loop drains the cells glutathione reserves, as the antioxidant is rapidly consumed in a desperate attempt to neutralize the surging ROS

Expert Opin Ther Targets 17:281291 Hartley JA (2011) The development of pyrrolobenzodiazepines as antitumour agents

Food supplements should not be used as a substitute for a varied diet or a healthy lifestyle