For preliminary studies or dose-finding experiments, starting at 7.5mg/kg provides a mid-range target that avoids both under-dosing (which produces false negatives) and excessive dosing (which increases off-target inflammation without improving efficacy).
People typically lost at least 20% of their body weight after a year of treatment
According to Healthline , vitamin B12 injections are considered generally safe, but some do have allergic reactions or sensitivity
Receptors for this hormone exist throughout the body, on immune cells, in the brain, in the cardiovascular system, in the kidneys, and in adipose tissue
This dosing far exceeds the recommended dietary allowance for vitamin B12 but is appropriate for injection therapy and ensures adequate B12 status even in patients with increased requirements or absorption issues