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When breaks make sense vs continuous use The decision between GHK-Cu cycling with breaks versus continuous indefinite application depends on individual goals, budget constraints, treatment response patterns, and philosophical approach to skincare interventions, with different strategies suiting different user profiles and priorities creating no single optimal approach applicable universally

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Previous studies have applied the standard Mini-International Neuropsychiatric Interview or the Hamilton Depression Rating Scale and the Beck Depression Inventory for evaluating the mood state of GD patients, which can be potential methods for assessing the patients' mental state (182)