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The peptide has been studied in laboratory and preclinical settings and is used in cosmetics, but it has not completed the FDA drug-approval process for a medical indication

GLP-1 receptor agonists: new game changing drugs in patients with heart failure with preserved ejection fraction and obesity

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Importantly, the differences in Ex4 and P5 in vivo efficacy are not due to differences in peptide pharmacokinetics as both peptides display similar half-life in mouse serum (supplementary Fig