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Milk fat globule-EGF factor 8 (MFG-E8) is an antifibrotic glycoprotein in MSC secretomes that strongly inhibits TGF signaling and reduces ECM deposition and liver fibrosis in mice [18]
Heterogeneity and penumbra of white matter hyperintensities in small vessel diseases determined by quantitative MRI
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Most importantly, they demonstrate efficacy against schistosome infections in mice, meeting the criteria for lead progression indicated by WHO, and outperform the previously reported efficacy of praziquantel against juvenile worms 13
J Agric Food Res 5:100182
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