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Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis

It has not progressed to extensive clinical trials, meaning its human safety and efficacy profile is not established it remains strictly a preclinical research compound

The disadvantage is that it depends entirely on individual gut health starting conditions, dietary habits, and microbiome composition, all of which vary dramatically between people

English search terms included: diabetic kidney disease OR diabetic nephropathy OR DKD OR DN, combined with gut microbiota OR gut microbiome OR intestinal flora OR intestinal microbiota, dietary OR nutrition OR diet OR nutritional intervention, phytochemical OR natural product OR bioactive compound OR functional food, amino acid metabolism OR metabolite OR metabolomics, gut-liver axis OR gut-kidney axis OR enterohepatic axis, short-chain fatty acids OR SCFAs, and probiotics OR prebiotics OR synbiotics. Inclusion criteria were: (1) studies addressing the associations among DKD, gut microbiota, nutritional intervention, and natural bioactive compounds

doi: 10.1111/jgh.13264 5