Medications requiring rapid gastrointestinal absorption for efficacy (e.g., oral contraceptives, antibiotics) should be taken at least 1 hour before exenatide injection
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means that it works by mimicking the effects of GLP-1, a hormone produced in the gut that stimulates insulin secretion, reduces glucagon secretion, and slows down gastric emptying
20 However, a retrospective single-institution study showed that although other anti-diabetic medications (such as sodium-glucose cotransporter 2 inhibitors) were associated with a lower risk of sight-threatening DR, GLP-1RAs were not shown to confer any increased DR risk, clinical worsening, or increased intervention in DR
Compounded semaglutide (vials) This is where 20 units becomes relevant and potentially dangerous
They apply across the entire class of peptide-based GLP-1 medications