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The relevance of the microbiota in the development of the central nervous system has been well demonstrated by previous studies using GF animals

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doi: 10.1016/j.cmet.2017.07.011 27 SchmittCPortronAJadidiSSarkarNDiMarchiR

Clinical Evidence Several clinical trials and studies underscore the cardiovascular benefits of GLP-1 receptor agonists: SUSTAIN-6 Trial : This pivotal trial demonstrated a significant reduction in major adverse cardiovascular events (MACE) among patients treated with GLP-1 compared to placebo

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