This stage is where the microbiome begins to shift and where foods that boost GLP-1 show more consistent effects for some people
doi: 10.3389/fcdhc.2025.1590530 Received 09 March 2025 Accepted 18 June 2025 Published 10 July 2025 Volume 6 - 2025 Edited by Angelo Maria Patti, University of Palermo, Italy Reviewed by Anapaula Sommer Vinagre, Federal University of Rio Grande do Sul, Brazil Jun Eguchi, Okayama University, Japan Updates Copyright 2025 Hammad, Zafar, Ullah, Faisal, Iftikhar, Waheed, Muzaffar, Ahmed, Ashraf, Zahid, Akhtar and Mahmmoud Fadelallah Eljack
1g, 2f, 6f, g, and Supplementary Fig
Regarding the participants with MCI or AD, defined based on a clinical dementia rating (CDR) global score of 0.5 or 1, although the 18-month treatment with exenatide was safe and well-tolerated, it did not significantly affect clinical and cognitive measures, nor did it affect MRI cortical thickness and volume or most biomarkers in the cerebrospinal fluid (CSF), plasma, and plasma neuronal extracellular vesicles (EVs)
GLP-1 medications provide significant heart protection by reducing inflammation, improving cholesterol profiles, and lowering the risk of heart failure and stroke
