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GSH participates in thiol-disulfide exchange through a reversible reaction catalyzed by thiol-transferases as shown below, where Protein-SSG is a mixed disulfide and Protein-SH is reduced protein: The thiol-disulfide equilibrium is determined by the redox state of the cell, which is based on GSH and GSSG concentrations

Slows Gastric Emptying: Keeps food in your stomach longer, creating prolonged feelings of fullness and reducing hunger between meals

They primarily function by reducing iron levels and inhibiting oxidative stress to prevent cell death (109111)

The foundational mechanism papers from the Washington State University lab were retracted in April 2025 after a misconduct finding of image manipulation

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