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These pigments possess a polyene backbone with conjugated double bonds, giving them strong antioxidant capabilities by quenching singlet oxygen and scavenging free radicals 188

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2.1.3.2 The GCH1/BH4/DHFR axis Guanosine triphosphate (GTP) cyclohydrolase 1 (GCH1) catalyzes the initial step in the biosynthesis of tetrahydrobiopterin (BH4), a process that also involves 6-pyruvyl tetrahydrobiopterin synthase (PTPS) and sepiapterin reductase (SPR)

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