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Phase 1 clinical trials of a selective rho kinase inhibitor, K-115

Ethical Approval No ethical approval is required for this study

This is described in the following pages

[36] Eglumetad has also been demonstrated to act on the metabotropic glutamate receptor 3 (GRM3) of human adrenocortical cells, downregulating aldosterone synthase, CYP11B1, and the production of adrenal steroids (i.e

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