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Once a fat cell is eliminated, it cannot regenerate, although remaining fat cells may expand if weight gain occurs

Patients using Contrave lost an average of 5% to 10% of their body weight over a year

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The beneficial role of tirzepatide on triglyceride levels could be at least partially explained by GIP-induced increased vascularization and lipid uptake in the adipose tissue [81]

At the same time, consistent anecdotal improvements shouldnt be dismissed outright especially in populations where conventional options have failed