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Mitochondrial function interference or mitochondrial damage is also one of the mechanisms of pathogenesis of PD (71)

Both T2DM and obesity are associated with a higher risk of cancer, which can be reduced by intentional weight loss, whereas effects of a reduction in hyperglycaemia are uncertain

Epidemiological evidence indicates an association between diabetes and Peyronies disease, with diabetes recognized as a risk factor for its development [43]

Crucially, the level of improvement was highest for the newest GLP-1 drugs, with tirzepatide performing best of all, consistent with Mounjaro and Zepbound patient reports