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Li et al., 2009

Philadelphia, PA: Lippincott Williams & Wilkins, 2002:837851

These categories differ in the magnitude and direction of receptor activation, enabling tailored therapeutic applications depending on disease mechanisms and required biological responses

Calico, a subsidiary of Googles parent Alphabet, was set up in 2013 with around $3.5 billion in investment, to develop interventions that extend human lifespan