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It is an essential nutrient, meaning that it cannot be synthesized by the body and must be obtained through diet or supplements

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It is a highly lipophilic molecule that can cross the blood-brain barrier (BBB) and specifically destroy dopaminergic neurons, thus MPTP is commonly used for establishment of various animal PD models ( In vitro PD models based on dopaminergic neuronal death are commonly used for identifying PD drug candidates

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