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In numerous animal studies, MOTS-c has demonstrated a remarkable ability to combat diet-induced insulin resistance and obesity

Appetite issues in cirrhosis, including decreased food intake and quality, stem from various factors

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Clinical studies have shown that the addition of thalidomide to the anti-TB treatment regimen resulted in substantial clinical and neuroradiological improvement, with a favorable safety profile and good tolerability in patients with tuberculous meningitis (TBM) [49]

The active fragment TB-500 retains the key LKKTET motif responsible for actin binding and most of these downstream effects