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Dapagliflozin added to usual care in individuals with type 2 diabetes mellitus with pre-existing cardiovascular disease: a 24-week, multicenter, randomized, double-blind, placebo-controlled study with a 28-week extension

Ectopic NRF2 expression was achieved with pLenti-CMV-NFE2L2-Puro (#181919, Addgene)

Long-term evidence indicates that GLP-1 therapies can provide sustained weight reduction, improvements in glycemic control, and favorable cardiometabolic changes when combined with lifestyle modifications and appropriate clinical follow-up

Cell lysates and basilar supernatants were run in 4%12% sodium dodecyl sulphatepolyacrylamide (SDS-PAGE) gels (Invitrogen) and transferred onto polyvinylidene difluoride membrane (Invitrogen)

This is particularly valuable for athletes and active individuals who require adequate caloric intake to support training demands