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FDA approval is not expected before late 2027

Animal studies show that the metabolites can be toxic to neurons at levels that are much lower than those required for liver damage.[ref][ref] I cant help but think that the times when you give an infant acetaminophen circumcision, shots, and illnesses are also the times when the antioxidant system is already taxed, bringing about two hits to their young detox system

Immunol Res (2012) 54:11120

Should metformin dose be increased first in a patient with type 2 diabetes mellitus, HbA1c 5.8%, taking metformin 500 mg daily, phentermine, and NP thyroid 60 mg daily, with poor diet and exercise compliance, before considering GLP-1 receptor agonists?