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Epub 2013 Mar 4

Are these improvements simply the result of weight loss, or do GLP-1 medications have direct anti-inflammatory and neuromodulatory effects

Even after weeks of dosing, no clinically meaningful accumulation occurs

Following the treatment course, the MASI score of the included patients was increased from 41.7% to 85%, however, the melasma severity scale (MSS) was decreased from moderate (score 2) to mild (score 1) during the treatment course (Kusumawardani et al., 2019)