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More research is needed to explore the link between the different genetic variants of G6PD and this alternate pathway in Heinz body catabolism that could possibly explain this hematological peculiarity

The mechanisms underlying these effects likely involve glutathione's role in reducing oxidative stress in metabolic tissues, supporting mitochondrial function and energy production, and modulating inflammatory pathways that affect metabolic regulation

OConnell, J

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112 DAN encompasses multiple subtypes, including cardiovascular autonomic neuropathy (CAN), gastrointestinal autonomic neuropathy, genitourinary autonomic neuropathy, sudomotor dysfunction, hypoglycemia unawareness, and pupillary dysfunction, each affecting different organ systems and presenting a spectrum of clinical manifestations