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Targeting the high-expression enzymes in cancer amino acid metabolism via small molecule inhibitors or RNAi-targeting approaches is emerging as a crucial therapy (Martinez-Outschoorn et al., 2017

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Scand J Gastroenterol 48:11521159

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However, the synthesis pathways of flavonoids are relatively numerous and complex, so we have briefly summarized a flowchart for a better understanding of flavonoid biosynthesis pathways ( Figure 7 )

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Wnt signaling in development and tissue homeostasis

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