This alternative cell death pathway offers potential in cancer therapy, especially in cases where cancer cells have developed resistance to apoptosis, by providing a new avenue to target and eliminate cancer cells through distinct biochemical and morphological mechanisms (Seo et al., 2023)
Effects of zinc status on age-related T cell dysfunction and chronic inflammation
Indeed, Mao and colleagues (283) found that global KO mice, in contrast to conditional -cell ZnT8 KO mice, exhibited adipocyte hypertrophy due to lipid accumulation in all major white adipose depots (VAT and SAT), accumulation of lipids in the liver, and increased expression of genes related to fatty acid synthesis and uptake
Science 297 , 811 (2002)
In a statement, it said the onus was on practitioners to do the right thing and follow good practice, including "only recommending treatments when there is an identified therapeutic need and a reasonable expectation of clinical efficacy and benefit"