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The drug works by inhibiting an enzyme called dihydrofolate reductase (DHFR), which plays a key role in the metabolic pathways that produce glutathione, as well as the pathways that produce new DNA bases

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Although this is a very experimental area at present

When people start developing thyroid antibodies, they may start to exhibit a number of different non-specific symptoms like fatigue , anxiety, stress, miscarriages, hair loss, weight gain, and a general feeling of being unwell

In addition, other symptoms that can be treated include behavior and mood alterations (e.g, depression, apathy, anxiety, etc.) which may manifest as decreased facial expression, decreased movement, a state of indifference, and quiet speech