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Weight Loss: The Data At this time, there arent any published head-to-head obesity trials directly comparing oral semaglutide to orforglipron, says Maria Teresa Anton, MD, a board-certified internal medicine physician who specializes in endocrinology, diabetes, and metabolism with Pritikin Longevity Center in Miami

Moreover, these agents possess anti-inflammatory and endothelial-protective properties, which may have implications for mitigating complications related to infections and systemic inflammation [22,23,24]

Dysesthesia in the trials was usually mild and resolved during ongoing treatment

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It also helps keep your metabolism running smoothly and your midsection lean