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[61] reported a significant increase in the expression of ferroptosis agonist protein and a significant decrease in the expression of ferroptosis inhibitor protein, as well as a significant increase in MDA levels in HK-2 cells with increasing CaOx concentration

5.3 Antidepressant and anxiolytic effects Elevated levels of systemic inflammation, neuroinflammation, and hyperactivity of the hypothalamicpituitaryadrenal (HPA) axis have been identified as key factors contributing to the pathogenesis of neuropsychiatric disorders, including depression and anxiety (7074)

CONCERN #10: WEAKENED IMMUNE DEFENSES Description: You seem to catch every cold that goes around, and it takes you longer to recover than others