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Nail changes were not assessed systematically in the IMPACT studies, but an open-label trial of infliximab in 18 patients with psoriasis or PsA and nail involvement demonstrated marked improvement over 38 weeks of therapy
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The wide specificity toward carnitine derivatives is very important in the regulation of their traffic and is in line with the detection of more than 100 different types of acylcarnitines in plasma and urine (Xiang et al., 2017)
This protective benefit was strongest among participants whose baseline systemic inflammation was at or above the fiftieth percentile
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