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J Biol Chem 251 : 42874293 Pisoni RL, Acker TL, Lisowski KM, Lemons RM, Thoene JG 1990 A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: possible role in supporting lysosomal proteolysis

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Dose Range: 5001000 mcg daily with gradual titration (~5 mg/week average)

Laboratory studies explore optimal administration regimens for different research objectives, including acute versus chronic senescent cell elimination and the effects of repeated administrations on tissue function and aging markers