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When to Seek Medical Attention for Fatigue While mild-to-moderate fatigue is expected, severe tiredness that prevents daily activities beyond week 3-4 warrants medical evaluation

Clinicians should take a thorough baseline musculoskeletal history before initiating any weight-management pharmacotherapy, including investigational agents such as retatrutide, to allow for meaningful comparison if symptoms arise during treatment

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No major prep is needed, but you can set yourself up for success with a few simple steps: Your provider will insert a small IV line and begin the NAD+ drip at a controlled pace