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10.3390/medsci7090096 98 ThomasC

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31 Vitamin B 12 deficiency leads to hematologic, neuropathologic, and cardiovascular disorders, mainly by interfering in the homocysteine (Hcy) metabolism and the methylation reactions of the organism

Therefore, in real life such melanocytomas are probably unrelated to the vast majority of classical (Clarks and McGoverns) ( Figure 1 shows a case of early superficial spreading melanoma over a combined BIN, with the malignant component being BAP1-positive, and being thus unrelated with the dermal melanocytoma

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