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In the study of Phillips et al

Clinical trials with LINGO-1 antagonists have provided encouraging preliminary results, at least for optic neuritis

Xenogenic stem cell suppression is based on the use of autologous hematopoietic stem cells to overcome complications that can be a limiting factor in allogeneic HSCT, such as donor availability, risk of infections, graft rejection, and graft-vs.-host disease (183193)