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The coverage that the multisite, multienzyme metabolism provides can be readily illustrated with the metabolism of the breast cancer chemotherapeutic drug, tamoxifen (Figure 2.6).

Without it, a generic company wins a patent case and enters a commodity market the same day as multiple competitors at 90% price erosion, sharing 100% of the market

Furthermore, activation of GLP-1R in BMSCs resulted in accumulation of nuclear -catenin, which upon association with TCF7L12 activated osteogenic genes [67]

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Para todos los parmetros, no se observ un patrn relevante en trminos de valores extremos (esto es, valores por debajo o por arriba del margen normal)