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Among the most advanced pharmacologic candidates are resmetirom, a highly liver-selective thyroid hormone receptor- (THR-) agonist, and semaglutide, a long-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA) already approved for diabetes and obesity

It shields liver cells from the harm that free radicals and pollutants can do

This dual-receptor activation enhances circulating IGF-1 levels and supports anabolic and metabolic processes 1-5

Few have explored the combined impact of sociodemographic, clinical, and patient-reported factors on both EQ-5D-5L index (preference-based) and EQ VAS (subjective) scores

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