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Graphical Abstract Similar content being viewed by others Introduction Long-term exposure to air pollution is associated with increased risk of cardiopulmonary and neurological diseases, cancer, and overall mortality [1]

Notably, the peptide stimulates 59% of these genes while suppressing 41%, suggesting a sophisticated regulatory mechanism rather than a blunt biological effect

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Its unique copper-binding properties make it a reference compound for studying redox-mediated cellular signalling and matrix remodelling pathways

Positional cloning of the mouse obese gene and its human homologue