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Based on efficacy results from prior studies, for the purpose of this trial SIM was considered equivalent to "placebo"

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It improves the viability of cardiomyocytes, diminishes apoptotic cells, suppresses caspase-3 activity, alleviates damage to mitochondrial membrane potential, and decreases the expression of ER stress-related apoptosis proteins

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Athletes who are required to have a TUE to use corticosteroids in-competition should apply for a TUE if the use of their medication will occur within the time periods established below