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We found that compared to vitamin C or glutathione single supplementation, acute vitamin C and glutathione complex supplementation in 12 middle-aged triathletes resulted in decreased carbon dioxide output, decreased heart rate, and positive improvements in skeletal muscle oxygenation during 90 min of cycling exercise at 70% VO 2max , as well as positive improvements in blood and biological antioxidant potential (BAP) and diacron reactive oxygen metabolite(dROM) [85]

Therefore, further large-scale clinical studies must be carried out to evaluate the dosage and duration of therapy with these phytochemicals and herbal drugs individually and in combination with other drugs to treat PCOS

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Plant Cell 6 , 17131729 (1994)