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Incidence and risk factors for the development of prolonged and severe intrahepatic cholestasis after liver transplantation

doi:10.5665/sleep.4408

Recent evidence has revealed that GLP1 receptors are present in the brain, including the hypothalamus and choroid plexus, suggesting potential direct effects on CSF production and ICP regulation [1, 2, 3]

Dysaesthesia has been reported in some clinical trials of semaglutide, including the STEP UP T2D trial of subcutaneous semaglutide, results of which showed that the adverse effect was more common with 7.2 mg doses (n=58 [18.9%] of 307) compared with 2.4 mg doses (n=five [4.9%] of 103)

A detailed medication review is described as part of that same workup