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GLP-1 agonists influence the gut by slowing motility as part of their systemic metabolic and appetite-regulating function

In the Drosophila model, muscle-specific disruption of the ETC slows down age-related muscle deterioration and prolongs lifespan [50]

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The evidence strongly supports implementing early response checkpoints at 4 weeks and prompt medication intervention for non-responders, challenging the traditional approach of prolonged behavioral therapy before pharmacological support

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