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Obesity and diabetes
Two major neuronal populations present in the arcuate nucleus control caloric intake and energy expenditure: one population co-expresses orexigenic agouti-related peptide (AgRP) and neuropeptide Y and the other expresses the anorexigenic anorectic neuropeptides proopiomelanocortin and cocaine- and amphetamine-regulated transcript (POMC/CART)
It does mean thyroid history is an important topic in any discussion of incretin-based treatment
Over a year, that adds up to more than $500 in overall savings while on GLP-1
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