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Plos One 14(9):16

Suga H, Sugaya M, Fujita H, Asano Y, Tada Y, Kadono T, et al

The affected endothelial cells undergo apoptosis

6.2 NADPH: driving force for glutathione redox cycling The antioxidant activity of glutathione (GSH) critically relies on its regeneration from the oxidized form, glutathione disulfide (GSSG), through a reaction catalyzed by glutathione reductase (GR) that consumes NADPH