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Human embryonic kidney (HEK) 293T cells recombinantly expressing human GIPR or cynomolgus monkey GIPR and Chinese hamster ovary (CHO) cells expressing rat or mouse GIPR were used to measure cyclic adenosine monophosphate (cAMP) accumulation

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Simultaneously, plasma 8-isoprostane, a specific biomarker indicating severe lipid peroxidation and damage to cell membranes, decreased by a massive 35%

Acknowledgements IAP acknowledges financial support from Empirikeion Foundation